Meet the AICRIstart PhD Students

Learn more about our ten PhD students, their projects
and interests. Coming from different backgrounds and cultures, the students represent a unique blend of talent and experience. 

Saoirse Flanagan

  • Hi, I’m Saoirse Flanagan, an Irish PhD student at the University of Limerick (UL), focusing on the field of non-small cell lung cancer (NSCLC) driven by the KRAS mutation.

    I am working under the guidance of Dr Catríona Dowling from the Royal College of Surgeons in Ireland, with Professor Paul Murray (University of Limerick) & Professor Jarushka Naidoo (Royal College of Surgeons in Ireland/Beaumont Hospital) as co-supervisors.

    My research aims to identify metabolic vulnerabilities associated with co-mutations, such as TP53 and LKB1, in NSCLC. By investigating these metabolic vulnerabilities and understanding their impact on clinical response, my project seeks to design innovative treatment options targeting these vulnerabilities. This research has the potential to pave the way for more personalised therapies, improving patient outcomes in aggressive KRAS-driven NSCLC.

  • Outside of my academic pursuits, I enjoys reading, painting, and listening to music. I have a particular passion for dogs and dream of using my hypothetical lottery winnings to rescue and care for animals in need. When it comes to food my favourite dish is a hearty roast dinner with plenty of roast potatoes.

  • I find the AICRIstart project truly exciting, especially because of the collaborative opportunities it brings. Being able to connect with fellow PhD students facing similar challenges has been a valuable and enjoyable experience. The project provides a supportive and friendly community that offers assistance whenever needed, making it an enriching and rewarding journey for me.

David Reck

  • Hello, I'm David Reck, an Irish PhD candidate at Trinity College Dublin. I am fortunate to be guided by Prof. Adrian Bracken as my supervisor, along with the support of Prof. William Gallagher from University College Dublin, who serves as my co-supervisor.

    My research project focuses on breast cancer and its genetic makeup. It's titled 'A Functional Investigation of Non-coding Driver Mutations in Breast Cancer and Associated Pathophysiological Impact.' Through this study, I aim to understand the intricate aspects of breast cancer and its underlying genetic mutations.

    Breast cancer continues to be a pressing health concern for women in Ireland, accounting for a significant portion of diagnosed female cancers and cancer-related deaths. While targeted therapies have shown promise in replacing traditional chemotherapy, there remains a subset of breast cancer patients without obvious gene mutations who still undergo chemotherapy, which comes with limited benefits and serious side effects. My research aims to tackle this challenge by focusing on the non-coding regions of the genetic material, where most mutations are found but are not well understood compared to protein-coding areas. By investigating newly discovered mutations in the non-coding regions that drive tumour growth, I plan to unravel how these mutations impact cancer-related gene expression. Ultimately, my goal is to develop innovative therapies and diagnostic methods tailored to breast cancer patients.

  • Beyond my academic pursuits, I like to play golf and tag-rugby. I enjoy the strategy these games require. My favourite food has to be a Sunday Roast with loads of potatoes and gravy.

  • I appreciate the AICRIstart project because of its emphasis on advancing cancer research and developing personalised treatments that can make a real difference in patients' lives. I also value the project's commitment to fostering collaboration among researchers from across the island of Ireland. Witnessing PhD students from various academic institutions collaborating on ground-breaking cancer research projects makes me feel hopeful for the future of cancer research.

Caoimbhe Burke

  • Hi, I’m Caoimbhe Burke, an Irish PhD candidate, pursuing my research at University College Dublin (UCD) under the guidance of Professor William Gallagher and Dr Arman Rahman. I’m supported by Professor Mark Tangney (UCC) and Professor Niamh Buckley (QUB), while I explore the field of microenvironmental changes in early-stage breast cancer.

    My PhD project, "Exploring Microenvironmental Changes in Early-Stage Breast Cancer Influencing Immune Infiltration and Reaction," addresses the need for improved recurrence risk prediction in breast cancer. By studying the bacteria and immune cells within breast cancer tissue, I aim to identify relevant markers and develop a predictive test for early-stage breast cancer.

  • Beyond my academic endeavours, I finds solace in reading and gardening.

    A fun fact about me is that I've managed to lead a Big Mac-free life! Yes, you heard it right—I've never had a taste of that iconic burger! Don't worry, I've had plenty of other delicious adventures on my plate!

    My favourite dish has to be my Nana's mince pies, a delightful family memory that brings warmth and nostalgia to my heart.

  • The AICRIstart project has provided me with valuable connections to fellow PhD students, allowing me to engage in insightful discussions and learn about diverse research areas. The access to resources and expertise across different Universities in Ireland is great. The community and the collaborative opportunities that the project has offered me has helped to enhance my own research, and contribute to the broader scientific community.

Shannon Kalsi

  • Hi! I'm Shannon Kalsi, a British PhD candidate conducting my research at the Royal College of Surgeons in Ireland (RCSI). My main focus is on exploring the molecular dissection of gene co-expression modules associated with brain metastasis in breast cancer. Guided by the expertise of Dr. Damir Vareslija and Professor Leonie Young from RCSI, and with the support of my co-supervisor Roisin Connolly from University College Cork, my goal is to identify brain-specific gene networks involved in the development of brain metastases. Through sample examinations and gene profiling, I aim to discover potential therapeutic targets for more effective treatment strategies.

  • Besides my research, I find joy in various activities such as archery, traveling, baking, and hitting the gym. As an amateur bird watcher, observing birds brings me a sense of delight. When it comes to food, my all-time favorite dish, representing my family's heritage, is Chole Masala with chapatti.

  • One aspect I really value about the AICRIstart project is its collaborative nature. It encourages researchers like myself to establish working relationships with peers and industry professionals on a national level, giving us a unique opportunity to temporarily step away from our host institutions and engage in fruitful collaborations. It's truly an enriching experience!

Abha Gupta

  • Hi there, I'm Abha Gupta, a passionate PhD candidate from India, currently pursuing my research journey at University College Cork. I'm lucky to have the guidance of Dr. Kellie Dean, and I also receive support from Prof. Róisín Connolly from University College Cork and Dr. Simon McDade from Queen's University Belfast.

    My PhD project, titled "Microproteins and Long Non-coding RNAs as Novel Biomarkers in Ovarian Cancer," delves into the challenging world of ovarian cancer. Given its tendency to be detected at advanced stages, ovarian cancer presents significant obstacles and often leads to poor outcomes for patients. My research focuses on identifying new classes of molecules, specifically long non-coding RNAs and associated microproteins, that play crucial roles in ovarian cancer. By unraveling the functions of these molecules within ovarian cancer cells, I aim to pave the way for the development of a reliable test for the early detection of ovarian cancer.

  • Apart from my academic pursuits, I find joy and self-expression through my love for singing. I have a knack for imitating the iconic voices of famous singers from both Bollywood and Hollywood, which allows me to showcase my versatility and admiration for the world of music. As for my favorite dish, Kadhai Paneer holds a special place in my heart. This flavorful and aromatic Indian delicacy represents my family's heritage and allows me to savor the rich and diverse flavors of Indian cuisine, evoking a sense of nostalgia and connection to my roots.

  • The AICRIstart project holds immense appeal for me, as it provides an outstanding platform for aspiring cancer biologists like myself to engage in groundbreaking research. The project offers invaluable support and resources that propel me forward in my pursuit of understanding and combating cancer. Moreover, I cherish the opportunity to connect and socialise with other AICRIStart PhD students. This vibrant community allows for the exchange of ideas, fostering an environment of collective learning and growth among contemporary early-stage cancer researchers. It's an inspiring and collaborative journey, and I'm thrilled to be a part of it!

Mohd Rifqi Rafsanjani

  • Hi, I'm Mohd Rifqi Rafsanjani, a Malaysian PhD candidate at TU Dublin (TUD). My research revolves around predicting subtyping and recurrence in colorectal cancer (CRC). With the guidance of Aidan D. Meade (TUDI), I'm determined to tackle the limitations of current prognostic methods using chemical spectroscopic imaging, particularly Fourier Transform Infrared (FTIR) imaging. My ultimate goal is to create a powerful pipeline that combines chemical imaging with transcriptomic data fusion to improve subtyping and recurrence prediction for stage II/III CRC patients. It's an exciting journey, and I can't wait to see where it leads!

  • I absolutely love photography, capturing moments and creating visual stories through my lens.

    A fun fact about me is that if I'm not engrossed in scientific pursuits, you might just find me daydreaming about becoming an architect. Beautifully designed structures and spaces have always intrigued me.

    Nasi lemak takes the crown as my all-time favorite dish. It's a Malaysian national delicacy that never fails to satisfy my taste buds with its delightful blend of flavours.

  • I really appreciate the AICRIstart project for the incredible collaborative opportunities it brings. Working alongside experts from various fields allows me to explore cancer research with an interdisciplinary approach. I firmly believe that combining diverse knowledge and expertise can pave the way for innovative solutions, ultimately leading to significant advancements in cancer prevention, diagnosis, and treatment. It's an exciting journey, and I'm thrilled to be part of such a promising endeavour!

Pippa Blevings

  • Hello, I'm a PhD candidate from outside of Belfast working jointly with Queen's University Belfast (QUB) and Trinity College Dublin (TCD). Under the guidance of Professor Christopher Scott from QUB and co-supervisor Professor Ed Lavelle from TCD, my PhD title is "The use of tumour-associated antigen nanoformulations to drive potent anti-tumour CD4 and CD8 T cell responses." In simpler terms, my project aims to develop a proof-of-concept mouse model to identify tumour-specific markers known as tumour-associated antigens (TAAs) and combine them with nanoparticles as an adjuvant in a vaccine for cancer immunotherapy, activating the body's own immune system to effectively treat tumours.

  • Besides research, I enjoy music, playing the piano and reading. I also love nature and animals and enjoy walking my dogs at the beach. My favourite dish from my family is Christmas dinner as lots of happy memories are attached to it.

  • Cancer patients should be at the core of cancer research. It's a privilege to be part of a multidisciplinary team of researchers brought together by the AICRIstart project, fostering collaboration between researchers from the North and South of Ireland. Together, we can make a difference in the fight against cancer.

Panagiotis Sarametidis

  • Hi, I'm Panagiotis (Panos) Sarametidis, a Greek PhD candidate at Dublin City University. I'm conducting my research under the guidance of Dr. Naomi Walsh at the same institute. My project is focused on exploring the therapeutic response prediction to immune checkpoint inhibitors (ICI) in homologous recombination deficient (HRD) pancreatic cancer.

    My research aims to investigate the effectiveness of immune checkpoint inhibitors in a pancreatic ductal adenocarcinoma organoid-immune co-culture system. This system will help us determine the response and resistance to PARP inhibitors and cisplatin. Additionally, I'm working on developing a novel blood-based predictive biomarker signature of response. By utilizing 3D cellular organoid models and incorporating immune features of the tumor microenvironment, my research enables preclinical testing of immunotherapy responses that accurately represent the cellular architecture and heterogeneity of pancreatic ductal adenocarcinoma in vivo.

  • Apart from my academic pursuits, I enjoy playing basketball and board games during my leisure time. And when it comes to food, my favourite dish that represents my family's heritage is mousakas.

  • The AICRIstart project holds great significance for me as it's a wonderful initiative that not only provides opportunities for students like myself to pursue their studies but also brings us together, fostering collaboration and support throughout our research journey. It's an inspiring platform that encourages innovation and empowers us to make a meaningful impact in the field of cancer research.

Sophie Carlin

  • Hi, I'm Sophie Carlin, an Irish PhD candidate at Ulster University and University College Dublin (UCD). My dedicated supervisors are Dr. Kyle Matchett from Ulster University and Prof. Jonathan Bond from UCD, with valuable co-supervision provided by Prof. Declan McKenna and Dr. Seodhna Lynch from Ulster University.

    In my PhD project titled "Developing Epigenetic Synergistic Drug Combinations with Albendazole in Paediatric Acute Myeloid Leukaemia," I am researching the challenges of acute myeloid leukaemia (AML). AML is an aggressive form of blood cancer affecting both children and adults, with poor survival outcomes and harsh treatments. My aim is to discover a gentler and less toxic treatment option for children with AML. I'm exploring the potential of repurposing Albendazole, a drug primarily used for worm infections, as a novel treatment for AML. This drug has shown promising anti-tumour effects in various cancers, offering a hopeful avenue for better treatment.

  • Outside of my research, I enjoy farming and working with animals, finding peace in nature. I love cooking and baking, whipping up delicious creations. Spending time with loved ones is dear to my heart, and I cherish moments with friends and family. I'm also an adventurous soul, eagerly exploring the beautiful landscapes of Ireland. As for my favourite dish, I have a soft spot for the classic Turkey and Ham Christmas dinner edition, a meal that reminds me of festive gatherings and cherished family traditions.

  • The AICRIstart project's appeal to me because of its ability to connect researchers across Ireland, fostering camaraderie and providing a platform for collaboration. Engaging with fellow researchers and learning about their projects has been inspiring and enriching. I'm excited to witness the progress and success of my peers within the AICRIstart project, as we collectively contribute to cancer research.

Abhishek Tomar

  • Hi, I'm Abhishek Tomar, an Indian PhD candidate at the Lambe Institute for Translational Research, University of Galway in Ireland. My research project titled "NEO-TIL-Developing durable novel TIL therapies for solid tumours with high tumour mutational burden" is my passion and focus. With the guidance of Dr. Laura Barkley and co-supervisor Professor Michael Kerin from the University of Galway, I am driven to unlock the potential of lymphocytes, a diverse group of immune cells with direct anti-cancer activity, found within metastatic solid tumors. My goal is to isolate and expand tumor-reactive lymphocytes from lung and breast cancer patients, envisioning the development of effective adoptive cell therapies for lung and breast cancer in Ireland.

  • Outside of research, I find joy in playing volleyball whenever I get the chance, and I also keep a keen eye on geopolitical events unfolding worldwide. As for my favourite dish representing my family's heritage, I have a soft spot for a variety of spicy North Indian delicacies, such as Dahl makhani and Aalu paratha. However, I must admit that the list could go on, given my appreciation for food.

  • I am particularly excited about the AICRIstart project, as it offers fantastic collaborative opportunities and allows me to connect with fellow researchers and professionals across Ireland. I believe that AICRIstart is just at the beginning and will continue to foster meaningful collaborations and make impactful contributions to the field of cancer research. It's a great journey, and I can't wait to see the possibilities that lie ahead!